Cerebral aneurysm

Summary about Disease


A cerebral aneurysm is a bulge or ballooning in a blood vessel in the brain. It often occurs at a branch point in an artery. Most cerebral aneurysms are small and don't cause any problems. However, an aneurysm can rupture, releasing blood into the space surrounding the brain (subarachnoid hemorrhage). This can lead to stroke, brain damage, or death.

Symptoms


Many unruptured aneurysms cause no symptoms, especially if they are small. Larger aneurysms may press on brain tissue and nerves, causing symptoms such as:

Headache

Vision changes

Numbness or weakness on one side of the face

Dilated pupil

Drooping eyelid

Pain above and behind one eye A ruptured aneurysm causes a sudden, severe headache often described as "the worst headache of my life." Other symptoms of a ruptured aneurysm include:

Nausea and vomiting

Stiff neck

Loss of consciousness

Seizures

Sensitivity to light (photophobia)

Confusion

Causes


The exact cause of cerebral aneurysms isn't fully understood, but several factors are believed to contribute:

Weakness in the artery wall: This can be present at birth (congenital) or develop over time.

High blood pressure: Chronic hypertension can weaken artery walls.

Atherosclerosis: The buildup of plaque in arteries can damage and weaken vessel walls.

Family history: Having a family history of aneurysms increases the risk.

Smoking: Smoking damages blood vessels.

Drug use: Particularly cocaine and amphetamines, which can raise blood pressure.

Traumatic head injury: Can damage blood vessels.

Certain inherited disorders: Such as Ehlers-Danlos syndrome, polycystic kidney disease, and Marfan syndrome.

Medicine Used


Medications for cerebral aneurysms depend on whether the aneurysm has ruptured or not, its size, and its location.

Unruptured Aneurysms:

Medications to control blood pressure: To reduce stress on the aneurysm wall.

Pain relievers: For headaches.

Statins: To help manage atherosclerosis.

Ruptured Aneurysms:

Nimodipine: A calcium channel blocker to prevent vasospasm (narrowing of blood vessels) after a subarachnoid hemorrhage.

Pain relievers: Stronger pain medications like opioids may be needed.

Anti-seizure medications: To prevent seizures.

Vasopressors: To increase blood pressure and improve blood flow to the brain.

Is Communicable


Cerebral aneurysms are not communicable. They are not caused by infectious agents and cannot be spread from person to person.

Precautions


Precautions focus on reducing the risk of aneurysm rupture or formation, especially for those with risk factors:

Control high blood pressure: Through medication, diet, and exercise.

Quit smoking: Smoking cessation is crucial.

Avoid drug use: Especially stimulants like cocaine and amphetamines.

Maintain a healthy weight: Obesity can contribute to high blood pressure and other risk factors.

Manage cholesterol levels: Through diet and medication if needed.

Regular checkups: For those with a family history of aneurysms or other risk factors.

Limit straining during bowel movements: Use stool softeners if needed.

Avoid heavy lifting: Or activities that significantly raise blood pressure.

Consider genetic counseling: If there is a strong family history of aneurysms.

How long does an outbreak last?


Cerebral aneurysms are not an outbreak related condition, but rather a chronic or acute disease. When an aneurysm ruptures, the resulting subarachnoid hemorrhage requires immediate treatment. Symptoms from a ruptured aneurysm or treatment complications, such as vasospasm, can last for weeks to months. Recovery time varies greatly depending on the severity of the bleed and the individual's overall health.

How is it diagnosed?


CT scan: Often the first test done to detect bleeding in the brain.

CT angiography (CTA): A CT scan with contrast dye to visualize blood vessels in the brain.

MRI: Provides detailed images of the brain and blood vessels.

Magnetic resonance angiography (MRA): An MRI with contrast dye to visualize blood vessels.

Cerebral angiogram (arteriogram): An invasive procedure where a catheter is inserted into an artery (usually in the groin) and guided to the brain to inject contrast dye and take X-ray images of the blood vessels. This is the "gold standard" for diagnosis.

Lumbar puncture (spinal tap): If a CT scan is negative but a ruptured aneurysm is suspected, a spinal tap can detect blood in the cerebrospinal fluid.

Timeline of Symptoms


This varies depending on whether the aneurysm is unruptured or ruptured.

Unruptured Aneurysm (if symptomatic):

Symptoms may develop gradually over time as the aneurysm grows and presses on surrounding structures.

Symptoms may be intermittent or constant, depending on the size and location of the aneurysm.

Ruptured Aneurysm:

Sudden onset: Symptoms appear abruptly, particularly the severe headache.

Within minutes to hours: Other symptoms like nausea, vomiting, stiff neck, loss of consciousness, and seizures may develop.

Days to weeks: Complications like vasospasm can occur, leading to new or worsening symptoms.

Important Considerations


Early detection is key: Finding and treating aneurysms before they rupture can prevent serious complications.

Treatment decisions are complex: The best course of action depends on the aneurysm's size, location, and the patient's overall health.

Long-term follow-up is necessary: After treatment, regular monitoring is important to detect any recurrence or complications.

Subarachnoid hemorrhage is a medical emergency: Prompt diagnosis and treatment are crucial for improving outcomes.

Psychological support: Both patients and their families may benefit from counseling and support groups.